Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals

The lck gene encodes a lymphocyte-specific protein-tyrosine kinase that is implicated in T cell maturation and signaling. In mammals, the transcription of the lck gene is regulated by two independent promoters, the proximal promoter, which is active in thymocytes, and the distal promoter, which domi...

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Main Authors: Brenner, Sydney, Venkatesh, Byrappa, Yap, Wai Ho, Chou, Chih-Fong, Tay, Alice, Ponniah, Sathivel, Wang, Yue, Tan, Y. H.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC122451/
https://ncbi.nlm.nih.gov/pubmed/11867707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032680599
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