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Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals

The lck gene encodes a lymphocyte-specific protein-tyrosine kinase that is implicated in T cell maturation and signaling. In mammals, the transcription of the lck gene is regulated by two independent promoters, the proximal promoter, which is active in thymocytes, and the distal promoter, which domi...

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Detalhes bibliográficos
Main Authors: Brenner, Sydney, Venkatesh, Byrappa, Yap, Wai Ho, Chou, Chih-Fong, Tay, Alice, Ponniah, Sathivel, Wang, Yue, Tan, Y. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122451/
https://ncbi.nlm.nih.gov/pubmed/11867707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032680599
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