A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2'-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction.

8-hydroxy-2'-deoxyguanosine (8OHdG) is a widely used biomarker for the measurement of endogenous oxidative DNA damage. A sensitive method for the quantification of 8OHdG in urine by single solid-phase extraction and GC-MS (gas chromatography with MS detection) using selective ion monitoring is...

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Detalhes bibliográficos
Main Authors: Lin, Hai-Shu, Jenner, Andrew M, Ong, Choon Nam, Huang, Shan Hong, Whiteman, Matthew, Halliwell, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224185/
https://ncbi.nlm.nih.gov/pubmed/14992687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040004
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