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Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.
Folding of newly synthesized proteins within the ER (endoplasmic reticulum) is a rate-limiting step in protein secretion. Thus ER molecular chaperones and foldases have a major impact in determining the rate and yield of these crucial cellular processes. Calnexin is a key ER chaperone implicated in...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224181/ https://ncbi.nlm.nih.gov/pubmed/14984369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031546 |
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