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Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.

Folding of newly synthesized proteins within the ER (endoplasmic reticulum) is a rate-limiting step in protein secretion. Thus ER molecular chaperones and foldases have a major impact in determining the rate and yield of these crucial cellular processes. Calnexin is a key ER chaperone implicated in...

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Main Authors: Maréchal, Alexandre, Tanguay, Pierre-Luc, Callejo, Mario, Guérin, Renée, Boileau, Guy, Rokeach, Luis A
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224181/
https://ncbi.nlm.nih.gov/pubmed/14984369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031546
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