SRC-dependent outside-in signalling is a key step in the process of autoregulation of beta2 integrins in polymorphonuclear cells.

In human PMN (polymorphonuclear cells), challenged by P-selectin, the beta2-integrin Mac-1 (macrophage antigen-1) promoted the activation of the SRC (cellular homologue of Rous sarcoma virus oncogenic protein) family members HCK (haematopoietic cell kinase) and LYN (an SRC family protein tyrosine ki...

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Hlavní autoři: Piccardoni, Paola, Manarini, Stefano, Federico, Lorenzo, Bagoly, Zsuzsa, Pecce, Romina, Martelli, Nicola, Piccoli, Antonio, Totani, Licia, Cerletti, Chiara, Evangelista, Virgilio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224154/
https://ncbi.nlm.nih.gov/pubmed/14969582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040151
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