Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling.

Nucling is a novel apoptosis-associated molecule, which is involved with cytochrome c /Apaf-1/caspase-9 apoptosome induction following pro-apoptotic stress. In the present study, we show first that Nucling is able to interact with galectin-3. Galectin-3 is known to participate in many biological pro...

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Bibliographic Details
Main Authors: Liu, Li, Sakai, Takashi, Sano, Nobuya, Fukui, Kiyoshi
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224150/
https://ncbi.nlm.nih.gov/pubmed/14961764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031300
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