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Identification and characterization of the conserved nucleoside-binding sites in the Epstein-Barr virus thymidine kinase.
Thymidine kinase (TK), encoded by EBV (Epstein-Barr virus), is an attractive target for antiviral therapy and provides a novel approach to the treatment of EBV-associated malignancies. Despite the extensive use of nucleoside analogues for the treatment of viral infections and cancer, the structure-f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224098/ https://ncbi.nlm.nih.gov/pubmed/14705959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031832 |
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