Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis.

Many commonly used drugs, such as psoralen and cisplatin, can generate a very unique type of DNA damage, namely ICL (interstrand cross-link). An ICL can severely block DNA replication and transcription and cause programmed cell death. The molecular mechanism of repairing the ICL damage has not been...

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Библиографические подробности
Главные авторы: Chen, Zhiwen, Xu, Xiaoxin Susan, Harrison, Jason, Wang, Gan
Формат: Artigo
Язык:Inglês
Опубликовано: 2004
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224063/
https://ncbi.nlm.nih.gov/pubmed/14728600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031143
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