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Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.

Previous studies have shown that human DHFR (dihydrofolate reductase), in addition to its critical role in DNA biosynthesis, functions as an RNA-binding protein. The interaction between DHFR and its own mRNA results in translational repression. In this study, we characterized the cis-acting elements...

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Bibliografiset tiedot
Päätekijät: Tai, Ningwen, Schmitz, John C, Chen, Tian-min, Chu, Edward
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224025/
https://ncbi.nlm.nih.gov/pubmed/14664697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031396
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