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Both N- and C-terminal regions are essential for cinnamomin A-chain to deadenylate ribosomal RNA and supercoiled double-stranded DNA.

Cinnamomin is a type II ribosome-inactivating protein and its A-chain exhibits RNA N-glycosidase activity to remove an adenine in the conserved sarcin/ricin loop of the largest RNA in ribosome, arresting protein synthesis at the elongation step. In this report, deadenylation of both rRNA and superco...

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Bibliografiske detaljer
Main Authors: He, Wen-Jun, Liu, Wang-Yi
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223831/
https://ncbi.nlm.nih.gov/pubmed/12952522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030703
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