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Both N- and C-terminal regions are essential for cinnamomin A-chain to deadenylate ribosomal RNA and supercoiled double-stranded DNA.
Cinnamomin is a type II ribosome-inactivating protein and its A-chain exhibits RNA N-glycosidase activity to remove an adenine in the conserved sarcin/ricin loop of the largest RNA in ribosome, arresting protein synthesis at the elongation step. In this report, deadenylation of both rRNA and superco...
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Main Authors: | , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2004
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223831/ https://ncbi.nlm.nih.gov/pubmed/12952522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030703 |
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