Alkylaminoquinolines inhibit the bacterial antibiotic efflux pump in multidrug-resistant clinical isolates.

Over the last decade, MDR (multidrug resistance) has increased worldwide in microbial pathogens by efflux mechanisms, leading to treatment failures in human infections. Several Gram-negative bacteria efflux pumps have been described. These proteinaceous channels are capable of expelling structurally...

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Detalhes bibliográficos
Main Authors: Malléa, Monique, Mahamoud, Abdallah, Chevalier, Jacqueline, Alibert-Franco, Sandrine, Brouant, Pierre, Barbe, Jacques, Pagès, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223807/
https://ncbi.nlm.nih.gov/pubmed/12959639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030963
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