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Induction of substrate specificity shifts by placement of alanine insertions within the consensus amphipathic region of the Escherichia coli GABA (gamma-aminobutyric acid) transporter encoded by gabP.

The Escherichia coli GABA (gamma-aminobutyric acid) permease GabP is a prototypical APC (amine/polyamine/choline) super-family transporter that has a CAR (consensus amphipathic region) containing multiple specificity determinants, ostensibly organized on two helical surfaces, one hydrophobic [SHS (s...

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Detalles Bibliográficos
Main Authors: King, Steven C, Hu, Liaoyuan A, Pugh, Amy
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223804/
https://ncbi.nlm.nih.gov/pubmed/12956623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030595
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