Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.

Proteins interacting with the human PDGF (platelet-derived growth factor) beta-receptor were isolated using immobilized peptides derived from the receptor C-terminus as a bait. We identified two PDZ domain proteins, namely NHERF (Na(+)/H(+) exchanger regulatory factor, also called EBP50) and NHERF2...

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Detalhes bibliográficos
Main Authors: Demoulin, Jean-Baptiste, Seo, Jeong Kon, Ekman, Simon, Grapengiesser, Eva, Hellman, Ulf, Rönnstrand, Lars, Heldin, Carl-Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223789/
https://ncbi.nlm.nih.gov/pubmed/12967325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030385
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