Processing, localization and binding activity of zonadhesin suggest a function in sperm adhesion to the zona pellucida during exocytosis of the acrosome.

Zonadhesin is a sperm protein that binds in a species-specific manner to the extracellular matrix ZP (zona pellucida) of the mammalian oocyte. The pig zonadhesin precursor is a 267000-Da mosaic protein with a Type I membrane topology and a large extracellular region comprising meprin/A5 antigen/mu r...

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Autori principali: Bi, Ming, Hickox, John R, Winfrey, Virginia P, Olson, Gary E, Hardy, Daniel M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223699/
https://ncbi.nlm.nih.gov/pubmed/12882646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030753
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