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Characterization of the interactions between Asp141 and Phe236 in the Mn2+-l-malate binding of pigeon liver malic enzyme.

The cytosolic malic enzyme from pigeon liver is very sensitive to the metal-catalysed oxidation systems. Our previous studies using the Cu2+-ascorbate as the oxidation system showed that the enzyme was oxidized and cleaved at several positions, including Asp141. The recently resolved crystal structu...

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Autors principals: Chen, Yen-I, Chen, Yu-Hou, Chou, Wei-Yuan, Chang, Gu-Gang
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223642/
https://ncbi.nlm.nih.gov/pubmed/12816540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030268
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