A novel protein phosphatase 2A (PP2A) is involved in the transformation of human protozoan parasite Trypanosoma cruzi.

Here we provide evidence for a critical role of PP2As (protein phosphatase 2As) in the transformation of Trypanosoma cruzi. In axenic medium at pH 5.0, trypomastigotes rapidly transform into amastigotes, a process blocked by okadaic acid, a potent PP2A inhibitor, at concentrations as low as 0.1 micr...

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Detalhes bibliográficos
Main Authors: González, Jorge, Cornejo, Alberto, Santos, Marcia R M, Cordero, Esteban M, Gutiérrez, Bessy, Porcile, Patricio, Mortara, Renato A, Sagua, Hernán, Da Silveira, José Franco, Araya, Jorge E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223626/
https://ncbi.nlm.nih.gov/pubmed/12737627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030215
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