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Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox.
Hsp90 (heat-shock protein 90) alone can act to prevent protein aggregation and promote refolding in vitro, but in vivo it operates as a part of a multichaperone complex, which includes Hsp70 and cohort proteins. Since the physiological function of Hsp90 is not yet fully understood, the development o...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223614/ https://ncbi.nlm.nih.gov/pubmed/12803546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030351 |
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