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Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions.

Basic fibroblast growth factor (FGF-2) is important in development, wound healing and angiogenesis. The human plasma proteinase inhibitor alpha2-macroglobulin (alpha2M) binds to and regulates the biological activity of various growth factors, including FGF-2. FGF-2 binds specifically and saturably t...

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Détails bibliographiques
Auteurs principaux: Mathew, Smitha, Arandjelovic, Sanja, Beyer, Wayne F, Gonias, Steven L, Pizzo, Salvatore V
Format: Artigo
Langue:Inglês
Publié: 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223577/
https://ncbi.nlm.nih.gov/pubmed/12755687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021655
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