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Pigment-epithelium-derived factor (PEDF) occurs at a physiologically relevant concentration in human blood: purification and characterization.

Pigment epithelium-derived factor (PEDF) inhibits the formation of blood vessels in the eye by inducing apotosis in actively dividing endothelial cells. The activity of PEDF equals or supersedes that of other anti-angiogenic factors, including angiostatin, endostatin and thrombospondin-1. In additio...

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Detalhes bibliográficos
Main Authors: Petersen, Steen V, Valnickova, Zuzana, Enghild, Jan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223568/
https://ncbi.nlm.nih.gov/pubmed/12737624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030313
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