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N-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2.

Within the C-terminal domain of many secretory mucins is a 'cystine knot' (CK), which is needed for dimer formation in the endoplasmic reticulum. Previous studies indicate that in addition to an unpaired cysteine, the three intramolecular cystine bonds of the knot are important for stabili...

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Detalhes bibliográficos
Main Authors: Bell, Sherilyn L, Xu, Gongqiao, Khatri, Ismat A, Wang, Rongquan, Rahman, Sameera, Forstner, Janet F
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223556/
https://ncbi.nlm.nih.gov/pubmed/12744721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030096
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