Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells

Here, we show that motexafin gadolinium (Gd-Tex), a compound that promotes intracellular oxidative stress, selectively induces apoptosis in HIV-1-infected CD4(+) T cells in IL-2-stimulated cultures of peripheral blood mononuclear cells infected in vitro with HIV-1. This selective induction of apopto...

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Détails bibliographiques
Auteurs principaux: Perez, Omar D., Nolan, Garry P., Magda, Darren, Miller, Richard A., Herzenberg, Leonard A., Herzenberg, Leonore A.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122354/
https://ncbi.nlm.nih.gov/pubmed/11854523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261711499
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