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The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase.

Microcystins are hepatotoxic, non-ribosomal peptides produced by several genera of freshwater cyanobacteria. Among other enzymic activities, in particular those of peptide synthetases and polyketide synthases, microcystin biosynthesis requires racemases that provide D-aspartate and D-glutamate. Here...

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Bibliographic Details
Main Authors: Sielaff, Heike, Dittmann, Elke, Tandeau De Marsac, Nicole, Bouchier, Christiane, Von Döhren, Hans, Börner, Thomas, Schwecke, Torsten
Format: Artigo
Language:Inglês
Published: 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223527/
https://ncbi.nlm.nih.gov/pubmed/12713441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030396
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