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Molecular specialization of breast vasculature: A breast-homing phage-displayed peptide binds to aminopeptidase P in breast vasculature

In vivo phage display identifies peptides that selectively home to the vasculature of individual organs, tissues, and tumors. Here we report the identification of a cyclic nonapeptide, CPGPEGAGC, which homes to normal breast tissue with a 100-fold selectivity over nontargeted phage. The homing of th...

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Detalhes bibliográficos
Main Authors: Essler, Markus, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122351/
https://ncbi.nlm.nih.gov/pubmed/11854520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251687998
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