A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).

Islet-cell antigen 512 (IA-2) and phogrin (IA-2beta) are atypical members of the receptor protein tyrosine phosphatase (PTP) family that are characterized by a lack of activity against conventional PTP substrates. The physiological role(s) of these proteins remain poorly defined, although recent stu...

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Detalhes bibliográficos
Main Authors: Drake, Paul G, Peters, Günther H, Andersen, Henrik Sune, Hendriks, Wiljan, Møller, Niels Peter H
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223505/
https://ncbi.nlm.nih.gov/pubmed/12697028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021851
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