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Heparan sulphate glycosaminoglycans derived from endothelial cells and smooth muscle cells differentially modulate fibroblast growth factor-2 biological activity through fibroblast growth factor receptor-1.

Fibroblast growth factor (FGF) signalling is involved in a wide range of important biological activities with differential effects in various cell types. The activity of FGF is modulated by heparin/heparan sulphate-like glycosaminoglycans (HSGAGs), found both in the extracellular matrix and on the c...

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Detalles Bibliográficos
Main Authors: Berry, David, Shriver, Zachary, Natke, Barbara, Kwan, Chi-Pong, Venkataraman, Ganesh, Sasisekharan, Ram
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223466/
https://ncbi.nlm.nih.gov/pubmed/12659634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021760
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