The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation.

Proteins containing PAAD [pyrin, AIM (absent-in-melanoma), ASC [apoptosis-associated speck-like protein containing a CARD (caspase-recruitment domain)] and DD (death domain)-like] (PYRIN, DAPIN) domains are involved in innate immunity, regulating pathways leading to nuclear-factor-kappa B (NF-kappa...

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Autores principales: Stehlik, Christian, Krajewska, Maryla, Welsh, Kate, Krajewski, Stanislaw, Godzik, Adam, Reed, John C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223462/
https://ncbi.nlm.nih.gov/pubmed/12656673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030304
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