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Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes.

To obtain information about the role of phosphoinositide 3-kinase (PI3K) in the endocytic pathway in hepatocytes, the uptake and intracellular transport of asialo-orosomucoid (ASOR) was followed in cells treated with wortmannin or LY294002. The two inhibitors, at concentrations known to inhibit the...

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Detalhes bibliográficos
Main Authors: Mousavi, Seyed Ali, Brech, Andreas, Berg, Trond, Kjeken, Rune
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223449/
https://ncbi.nlm.nih.gov/pubmed/12646047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021136
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