Insulin and dexamethasone induce GLUT4 gene expression in foetal brown adipocytes: synergistic effect through CCAAT/enhancer-binding protein alpha.

Treatment of foetal brown adipocytes in primary culture with either dexamethasone or insulin, at physiological concentrations, for 24 h up-regulates the expression of the GLUT4 gene, producing a synergistic effect on mRNA accumulation (20-fold increase), in the amount of protein in the total membran...

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Main Authors: Hernandez, Rosario, Teruel, Teresa, Lorenzo, Margarita
Formato: Artigo
Idioma:Inglês
Publicado: 2003
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223428/
https://ncbi.nlm.nih.gov/pubmed/12641495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030325
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