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Haem and nitric oxide: synergism in the modulation of the endothelial haem oxygenase-1 pathway.
NO potently up-regulates vascular haem oxygenase-1 (HO-1), an inducible defensive protein that degrades haem to CO, iron and the antioxidant bilirubin. Since several pathological states are characterized by increased NO production and liberation of haem from haem-containing proteins, we examined how...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223420/ https://ncbi.nlm.nih.gov/pubmed/12622689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021516 |
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