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Haem and nitric oxide: synergism in the modulation of the endothelial haem oxygenase-1 pathway.

NO potently up-regulates vascular haem oxygenase-1 (HO-1), an inducible defensive protein that degrades haem to CO, iron and the antioxidant bilirubin. Since several pathological states are characterized by increased NO production and liberation of haem from haem-containing proteins, we examined how...

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Autors principals: Foresti, Roberta, Hoque, Martha, Bains, Sandip, Green, Colin J, Motterlini, Roberto
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223420/
https://ncbi.nlm.nih.gov/pubmed/12622689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021516
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