Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylglucosaminidase.

We have previously reported three Caenorhabditis elegans genes ( gly-12, gly-13 and gly-14 ) encoding UDP- N -acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2- N -acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid and complex N-glycan synthesis. GLY-13 was shown to be the major...

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Detalhes bibliográficos
Main Authors: Zhang, Wenli, Cao, Pinjiang, Chen, Shihao, Spence, Andrew M, Zhu, Shaoxian, Staudacher, Erika, Schachter, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223384/
https://ncbi.nlm.nih.gov/pubmed/12603202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021931
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