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Characterization of SUMO-conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant-negative allele that severely reduces SUMO conjugation.

The phenotypes of mutants defective in the Schizosaccharomyces pombe SUMO (small, ubiquitin-like modifier)-conjugating enzyme Hus5 (the homologue of Ubc9) show that it is required for recovery from S-phase arrest. Unlike the case with ubiquitination, where ligases are required, SUMO-conjugating enzy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ho, Jenny C Y, Watts, Felicity Z
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223380/
https://ncbi.nlm.nih.gov/pubmed/12597774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021645
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