Pim serine/threonine kinases regulate the stability of Socs-1 protein

Studies of SOCS-1-deficient mice have implicated Socs-1 in the suppression of JAK-STAT (Janus tyrosine kinase-signal transducers and activators of transcription) signaling and T cell development. It has been suggested that the levels of Socs-1 protein may be regulated through the proteasome pathway....

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Main Authors: Chen, X. Peter, Losman, Julie A., Cowan, Simone, Donahue, Elizabeth, Fay, Scott, Vuong, Bao Q., Nawijn, Martijn C., Capece, Danielle, Cohan, Victoria L., Rothman, Paul
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC122338/
https://ncbi.nlm.nih.gov/pubmed/11854514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042035699
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