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Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase.

We demonstrated that mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) first suppressed the dissociation of cytochrome c (cyt c) from cardiolipin (CL) in mitochondrial inner membranes and then apoptosis caused by the hypoglycaemia by the prevention of peroxidation of CL [Nomura...

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Detalhes bibliográficos
Main Authors: Imai, Hirotaka, Koumura, Tomoko, Nakajima, Ryo, Nomura, Kazuhiro, Nakagawa, Yasuhito
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223322/
https://ncbi.nlm.nih.gov/pubmed/12534348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021342
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