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3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin.

Cytotoxic polyamine-derived amino aldehydes, formed during cerebral ischaemia, damage adjacent tissue (the so-called 'penumbra') not subject to the initial ischaemic insult. One such product is 3-aminopropanal (3-AP), a potent cytotoxin that accumulates in ischaemic brain, although the pre...

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Autors principals: Li, Wei, Yuan, Xi-Ming, Ivanova, Svetlana, Tracey, Kevin J, Eaton, John W, Brunk, Ulf T
Format: Artigo
Idioma:Inglês
Publicat: 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223282/
https://ncbi.nlm.nih.gov/pubmed/12513695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021520
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