Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.

In Bacillus megaterium, the hemAXBCDL genes were isolated and were found to be highly similar to the genes from Bacillus subtilis that are required for the conversion of glutamyl-tRNA into uroporphyrinogen III. Overproduction and purification of HemC (porphobilinogen deaminase) and -D (uroporphyrino...

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Detalhes bibliográficos
Main Authors: Raux, Evelyne, Leech, Helen K, Beck, Richard, Schubert, Heidi L, Santander, Patricio J, Roessner, Charles A, Scott, A Ian, Martens, Jan H, Jahn, Dieter, Thermes, Claude, Rambach, Alain, Warren, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223173/
https://ncbi.nlm.nih.gov/pubmed/12408752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021443
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