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Distance of sequons to the C-terminus influences the cellular N-glycosylation of the prion protein.

Cell-specific differences in the utilization of the two N-glycosylation sequons (Asn180-Ile-Thr and Asn196-Phe-Thr) of the prion protein (PrP) have been proposed to influence the aetiology of the neurodegenerative prion diseases. As the N-glycosylation of PrP is ablated by deletion of the C-terminal...

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Detaylı Bibliyografya
Asıl Yazarlar: Walmsley, Adrian R, Hooper, Nigel M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223167/
https://ncbi.nlm.nih.gov/pubmed/12460122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021303
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