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Ceramide 1-phosphate increases intracellular free calcium concentrations in thyroid FRTL-5 cells: evidence for an effect mediated by inositol 1,4,5-trisphosphate and intracellular sphingosine 1-phosphate.

Sphingolipid (SP) derivatives have diverse effects on the regulation of intracellular free calcium concentrations ([Ca2+]i) in a multitude of non-excitable cells. In the present investigation, the effect of C2-ceramide 1-phosphate (C1P) on [Ca2+]i was investigated in thyroid FRTL-5 cells. C1P evoked...

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Detalhes bibliográficos
Main Authors: Högback, Susanna, Leppimäki, Petra, Rudnäs, Britt, Björklund, Sonja, Slotte, J Peter, Törnquist, Kid
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223145/
https://ncbi.nlm.nih.gov/pubmed/12416995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020970
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