Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting.

Apolipoprotein (apo) B mRNA editing is the deamination of C(6666) to uridine, which results in translation of the apoB-48 protein instead of the genomically encoded apoB-100. ApoB-48-containing lipoproteins are cleared more rapidly from plasma and are less atherogenic than apoB-100-containing low-de...

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Detalhes bibliográficos
Main Authors: Hersberger, Martin, Patarroyo-White, Susannah, Qian, Xiaobing, Arnold, Kay S, Rohrer, Lucia, Balestra, Maureen E, Innerarity, Thomas L
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223090/
https://ncbi.nlm.nih.gov/pubmed/12374571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020694
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