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Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport.

Regulation of sterol regulatory element-binding proteins (SREBPs) by fatty acid flux was investigated in CaCo-2 cells. Cells were incubated with 1 mM taurocholate with or without 250 microM 18:0, 18:1, 18:2, 20:4, 20:5 or 22:6 fatty acids. Fatty acid synthase (FAS) and acetyl-CoA carboxylase mRNA le...

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Bibliografiske detaljer
Main Authors: Field, F Jeffrey, Born, Ella, Murthy, Shubha, Mathur, Satya N
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223029/
https://ncbi.nlm.nih.gov/pubmed/12213084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020731
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