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Synthesis and secretion of Muc4/sialomucin complex: implication of intracellular proteolysis.

Muc4/sialomucin complex (SMC) is a heterodimeric glycoprotein complex implicated in epithelial protection and overexpressed in some tumours. It is encoded by a single gene, and the two subunits are produced by proteolytic cleavage at a time before substantial O-glycosylation, near the time of transi...

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Autors principals: Komatsu, Masanobu, Arango, Maria E, Carraway, Kermit L
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222983/
https://ncbi.nlm.nih.gov/pubmed/12186632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020862
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