Extracellular signal-regulated protein kinase activation during reoxygenation is required to restore ischaemia-induced endothelial barrier failure.

During an ischaemic insult, oedema formation occurs as a consequence of increased vascular permeability. To study mechanisms leading to vascular barrier failure, endothelial cells were exposed to ischaemia (1% O(2) in serum- and glucose-free medium) for 5 h. In in vitro conditions, ischaemia increas...

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Hlavní autoři: Wachtel, Marco, Frei, Karl, Ehler, Elisabeth, Bauer, Christian, Gassmann, Max, Gloor, Sergio M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222922/
https://ncbi.nlm.nih.gov/pubmed/12137564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020746
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