Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo.

Intracellular targeting of the Pseudomonas aeruginosa toxins exoenzyme S (ExoS) and exoenzyme T (ExoT) initially results in disruption of the actin microfilament structure of eukaryotic cells. ExoS and ExoT are bifunctional cytotoxins, with N-terminal GTPase-activating protein (GAP) and C-terminal A...

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Main Authors: Henriksson, Maria L, Sundin, Charlotta, Jansson, Anna L, Forsberg, Ake, Palmer, Ruth H, Hallberg, Bengt
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222916/
https://ncbi.nlm.nih.gov/pubmed/12132999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020714
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