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Transport of a neurotoxicant by molecular mimicry: the methylmercury-L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2.

Methylmercury (MeHg) readily crosses cell membrane barriers to reach its target tissue, the brain. Although it is generally assumed that this rapid transport is due to simple diffusion, recent studies have demonstrated that MeHg is transported as a hydrophilic complex, and possibly as an L-cysteine...

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Bibliografische gegevens
Hoofdauteurs: Simmons-Willis, Tracey A, Koh, Albert S, Clarkson, Thomas W, Ballatori, Nazzareno
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222880/
https://ncbi.nlm.nih.gov/pubmed/12117417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020841
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