The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF).

Nardilysin (N-arginine dibasic convertase, or NRDc) is a cytosolic and cell-surface metalloendopeptidase that, in vitro, cleaves substrates upstream of Arg or Lys in basic pairs. NRDc differs from most of the other members of the M16 family of metalloendopeptidases by a 90 amino acid acidic domain (...

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Autores principales: Hospital, Véronique, Nishi, Eiichiro, Klagsbrun, Michael, Cohen, Paul, Seidah, Nabil G, Prat, Annik
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222870/
https://ncbi.nlm.nih.gov/pubmed/12095415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020822
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