Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.

A series of fumarate analogues has been used to explore the molecular mechanism of the activation of dopamine beta-mono-oxygenase by fumarate. Mesaconic acid (MA) and trans -glutaconic acid (TGA) both activate the enzyme at low concentrations, similar to fumarate. However, unlike fumarate, TGA and M...

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Detalhes bibliográficos
Main Authors: Wimalasena, D Shyamali, Jayatillake, Samantha P, Haines, Donovan C, Wimalasena, Kandatege
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222850/
https://ncbi.nlm.nih.gov/pubmed/12038965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020216
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