Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator.

Insulin regulates cellular metabolism and growth through activation of insulin receptors (IRs). We recently identified a non-peptide small-molecule IR activator (compound 2), which induced human IR tyrosine kinase activity in Chinese-hamster ovary cells expressing human IR [Qureshi, Ding, Li, Szalko...

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Detalhes bibliográficos
Main Authors: Ding, Victor D H, Qureshi, Sajjad A, Szalkowski, Deborah, Li, Zhihua, Biazzo-Ashnault, Dawn E, Xie, Dan, Liu, Kun, Jones, A Brian, Moller, David E, Zhang, Bei B
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222849/
https://ncbi.nlm.nih.gov/pubmed/12036431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020708
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