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Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo.

Rho GTPases control a complex network of intracellular signalling pathways. Whereas progress has been made in identifying downstream signalling partners for these proteins, the characterization of Rho upstream regulatory guanine-nucleotide exchange factors (GEFs) has been hampered by a lack of suita...

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Detalles Bibliográficos
Main Authors: Gampel, Alexandra, Mellor, Harry
Formato: Artigo
Idioma:Inglês
Publicado: 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222811/
https://ncbi.nlm.nih.gov/pubmed/12113653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020844
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