A peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama V(HH) domain.

The X-ray structure of a ternary complex between human chorionic gonadotropin hormone (hCG) and two Fvs recognizing its alpha and beta subunits has been recently determined. The Fvs recognize the elongated hCG molecule by its two ends, one being the Leu-12-Cys-29 loop of the alpha subunit. We have d...

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Main Authors: Ferrat, Gilles, Renisio, Jean-Guillaume, Morelli, Xavier, Slootstra, Jerry, Meloen, Rob, Cambillau, Christian, Darbon, Hervé
Formato: Artigo
Idioma:Inglês
Publicado: 2002
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222782/
https://ncbi.nlm.nih.gov/pubmed/11996668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020172
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