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Macrophage uptake of low-density lipoprotein bound to aggregated C-reactive protein: possible mechanism of foam-cell formation in atherosclerotic lesions.

Foam cells found in atherosclerotic lesions are believed to derive from macrophages that take up aggregated low-density lipoprotein (LDL) particles bound to the extracellular matrix of arterial walls. C-reactive protein (CRP) is an acute-phase protein found in atherosclerotic lesions, which when imm...

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Detalhes bibliográficos
Main Authors: Fu, Tao, Borensztajn, Jayme
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222776/
https://ncbi.nlm.nih.gov/pubmed/12033985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020045
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