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Multiple isoforms of mitochondrial glutathione S-transferases and their differential induction under oxidative stress.
The mitochondrial respiratory chain, which consumes approx. 85-90% of the oxygen utilized by cells, is a major source of reactive oxygen species (ROS). Mitochondrial genetic and biosynthetic systems are highly susceptible to ROS toxicity. Intramitochondrial glutathione (GSH) is a major defence again...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1222767/ https://ncbi.nlm.nih.gov/pubmed/12020353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020533 |
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