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Selenium deficiency increases the expression of inducible nitric oxide synthase in RAW 264.7 macrophages: role of nuclear factor-kappaB in up-regulation.

The inducible isoform of nitric oxide synthase (iNOS) is implicated in atherosclerosis, malignancy, rheumatoid arthritis, tissue and reperfusion injuries. A key determinant of the pro-oxidant versus protective effects of NO is the underlying redox status of the tissue. Selenoproteins, such as glutat...

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Detalhes bibliográficos
Main Authors: Prabhu, K Sandeep, Zamamiri-Davis, Faith, Stewart, Jennifer B, Thompson, Jerry T, Sordillo, Lorraine M, Reddy, C Channa
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222757/
https://ncbi.nlm.nih.gov/pubmed/12006087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020256
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